ABC News medical contributor Dr. Darien Sutton summarizes new research suggesting that taking a daily multivitamin may slightly slow biological aging. Published March 17, 2026, the study compared people who regularly took multivitamins with those who did not, using epigenetic clocks — patterns of DNA methylation that estimate biological age — as the outcome measure.
Investigators found a small but statistically significant reduction in estimated biological age among habitual multivitamin users over the study period. Authors propose plausible mechanisms, including improved antioxidant defenses, support for DNA repair pathways, and metabolic cofactor effects, that could account for the association.
Experts emphasize caution in interpreting the findings. Key limitations include relatively short follow-up, the possibility of residual differences between groups that were not fully controlled, and uncertainty about which specific nutrients, combinations, or doses might be responsible. Epigenetic clocks are evolving research tools, and shifts in these biomarkers do not automatically translate to lower disease risk or longer lifespan.
Practical takeaways: multivitamins can help fill nutrient gaps for people with restrictive diets or documented deficiencies, but they are not established longevity therapies. Dr. Sutton advises consulting a healthcare provider before starting supplements, since some vitamins can interact with medications or cause harm at high doses.
Researchers call for larger, longer randomized trials to confirm the signal, identify effective formulations and dosages, and determine whether changes in epigenetic markers lead to meaningful health or lifespan benefits. For now, proven strategies to support healthier aging remain a balanced diet, regular physical activity, adequate sleep, and avoiding tobacco.